Center for iPS Cell Research and Application (CiRA)

Human ‘blastoids’ offer medical hope but also deep ethical challenges

Human ‘blastoids’ offer medical hope but also deep ethical challenges

A study using an organ-on-a-chip reveals a mechanism of SARS-CoV-2 invasion into blood vessels ~Disruption of vascular endothelial barrier in respiratory organs by decreasing Claudin-5 expression~

A study using an organ-on-a-chip reveals a mechanism of SARS-CoV-2 invasion into blood vessels ~Disruption of vascular endothelial barrier in respiratory organs by decreasing Claudin-5 expression~

A new method for inducing mesenchymal stem cells from iPS cells without using animal-derived components

A new method for inducing mesenchymal stem cells from iPS cells without using animal-derived components

New Method for Cell Sorting Utilizing microRNA Switch and Magnetic Microbeads

New Method for Cell Sorting Utilizing microRNA Switch and Magnetic Microbeads

COVID-19 Research Using Bronchial Organoids and Drug Discovery Applications

COVID-19 Research Using Bronchial Organoids and Drug Discovery Applications

Invention of technology to create mature skeletal muscle cells from iPS cells without genetic manipulation

Invention of technology to create mature skeletal muscle cells from iPS cells without genetic manipulation

ALS-related protein TDP-43 regulates cholesterol synthesis ~Insight for molecular mechanisms of lipid metabolism and nutritional therapy in ALS~

ALS-related protein TDP-43 regulates cholesterol synthesis ~Insight for molecular mechanisms of lipid metabolism and nutritional therapy in ALS~

Discovery of genes required for survival of human iPS and ES cells

Discovery of genes required for survival of human iPS and ES cells

Microwell bag culture for large-scale production of homogeneous islet-like cell clusters

Microwell bag culture for large-scale production of homogeneous islet-like cell clusters

Financial risks posed by unproven cell interventions in Japan

Financial risks posed by unproven cell interventions in Japan

Single-cell RNA sequencing of hiPSC-derived muscle progenitor cells identifies key factors of proliferation

Single-cell RNA sequencing of hiPSC-derived muscle progenitor cells identifies key factors of proliferation

Elimination of non-target cells mixed into islet-like cells generated from human iPS cells based on characterization.

Elimination of non-target cells mixed into islet-like cells generated from human iPS cells based on characterization.

Dissection of the polygenic architecture using iPSC lines derived from Alzheimer's disease

Dirt can modulate the pathology in Alzheimer's disease

Using stem cells to regenerate the heart

Synthetic gene circuits that improve stem cell quality